Physical Properties | | | |
Molecular Weight: 414.869 g/mol | logS: -6.5319 | SlogP: 4.2026 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0476761 | Sterimol/B1: 2.5179 | Sterimol/B2: 3.41608 | Sterimol/B3: 3.81747 |
Sterimol/B4: 10.9642 | Sterimol/L: 17.2548 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 639.366 | Positive charged surface: 302.141 | Negative charged surface: 337.225 | Volume: 348.75 |
Hydrophobic surface: 455.972 | Hydrophilic surface: 183.394 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |