Physical Properties | | | |
Molecular Weight: 450.586 g/mol | logS: -7.78879 | SlogP: 6.41112 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.156772 | Sterimol/B1: 3.39759 | Sterimol/B2: 4.00971 | Sterimol/B3: 7.01867 |
Sterimol/B4: 7.76556 | Sterimol/L: 19.3217 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 769.381 | Positive charged surface: 458.154 | Negative charged surface: 311.228 | Volume: 458.875 |
Hydrophobic surface: 656.541 | Hydrophilic surface: 112.84 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |