Physical Properties | | | |
Molecular Weight: 422.521 g/mol | logS: -5.09706 | SlogP: 5.0361 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0952118 | Sterimol/B1: 2.82555 | Sterimol/B2: 5.08244 | Sterimol/B3: 5.49289 |
Sterimol/B4: 7.45326 | Sterimol/L: 17.7591 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 672.57 | Positive charged surface: 507.378 | Negative charged surface: 165.192 | Volume: 414 |
Hydrophobic surface: 594.758 | Hydrophilic surface: 77.812 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |