Physical Properties | | | |
Molecular Weight: 430.409 g/mol | logS: -4.35747 | SlogP: 3.0792 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0459331 | Sterimol/B1: 2.63418 | Sterimol/B2: 2.87238 | Sterimol/B3: 4.47426 |
Sterimol/B4: 10.4762 | Sterimol/L: 20.9203 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 725.203 | Positive charged surface: 446.847 | Negative charged surface: 278.357 | Volume: 382 |
Hydrophobic surface: 551.496 | Hydrophilic surface: 173.707 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |