Physical Properties | | | |
Molecular Weight: 602.772 g/mol | logS: -10.6388 | SlogP: 8.0915 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0455111 | Sterimol/B1: 2.40404 | Sterimol/B2: 3.58054 | Sterimol/B3: 5.74874 |
Sterimol/B4: 14.7365 | Sterimol/L: 26.5996 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 1037.19 | Positive charged surface: 694.658 | Negative charged surface: 342.529 | Volume: 603.875 |
Hydrophobic surface: 763.435 | Hydrophilic surface: 273.755 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |