Physical Properties | | | |
Molecular Weight: 443.412 g/mol | logS: -4.75321 | SlogP: 1.6548 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0323189 | Sterimol/B1: 2.73368 | Sterimol/B2: 3.48542 | Sterimol/B3: 4.01704 |
Sterimol/B4: 8.19276 | Sterimol/L: 23.5615 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 746.058 | Positive charged surface: 422.509 | Negative charged surface: 323.549 | Volume: 390.125 |
Hydrophobic surface: 505.401 | Hydrophilic surface: 240.657 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |