Physical Properties | | | |
Molecular Weight: 522.622 g/mol | logS: -6.41577 | SlogP: 4.35367 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.11519 | Sterimol/B1: 2.44189 | Sterimol/B2: 2.96308 | Sterimol/B3: 6.91875 |
Sterimol/B4: 12.3157 | Sterimol/L: 17.5322 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 868.209 | Positive charged surface: 542.683 | Negative charged surface: 325.526 | Volume: 496.5 |
Hydrophobic surface: 691.545 | Hydrophilic surface: 176.664 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |