Physical Properties | | | |
Molecular Weight: 452.844 g/mol | logS: -2.20394 | SlogP: -0.3925 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.320144 | Sterimol/B1: 3.78881 | Sterimol/B2: 4.78915 | Sterimol/B3: 6.21927 |
Sterimol/B4: 7.58238 | Sterimol/L: 17.2598 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 721.915 | Positive charged surface: 429.634 | Negative charged surface: 292.281 | Volume: 387.125 |
Hydrophobic surface: 469.119 | Hydrophilic surface: 252.796 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |