Physical Properties | | | |
Molecular Weight: 365.766 g/mol | logS: -1.95455 | SlogP: 0.3012 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.216045 | Sterimol/B1: 3.14565 | Sterimol/B2: 3.59865 | Sterimol/B3: 6.05985 |
Sterimol/B4: 6.64879 | Sterimol/L: 15.1562 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 579.964 | Positive charged surface: 324.67 | Negative charged surface: 255.294 | Volume: 312 |
Hydrophobic surface: 381.48 | Hydrophilic surface: 198.484 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |