Physical Properties | | | |
Molecular Weight: 391.441 g/mol | logS: -2.50836 | SlogP: 0.3956 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.173045 | Sterimol/B1: 2.39956 | Sterimol/B2: 2.54906 | Sterimol/B3: 5.83186 |
Sterimol/B4: 10.7584 | Sterimol/L: 15.8884 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 661.924 | Positive charged surface: 423.73 | Negative charged surface: 238.194 | Volume: 355.375 |
Hydrophobic surface: 480.458 | Hydrophilic surface: 181.466 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |