Physical Properties | | | |
Molecular Weight: 410.358 g/mol | logS: -3.99486 | SlogP: 0.69322 | Reactive groups: 1 |
| | | |
Topological Properties | | | |
Globularity: 0.124412 | Sterimol/B1: 2.39338 | Sterimol/B2: 4.01646 | Sterimol/B3: 6.12109 |
Sterimol/B4: 7.48632 | Sterimol/L: 16.2112 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 636.739 | Positive charged surface: 393.541 | Negative charged surface: 243.198 | Volume: 346.75 |
Hydrophobic surface: 476.318 | Hydrophilic surface: 160.421 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |