Physical Properties | | | |
Molecular Weight: 581.601 g/mol | logS: -6.84291 | SlogP: 3.6348 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.105129 | Sterimol/B1: 3.28854 | Sterimol/B2: 4.27968 | Sterimol/B3: 4.59754 |
Sterimol/B4: 12.2131 | Sterimol/L: 19.4976 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 889.308 | Positive charged surface: 545.902 | Negative charged surface: 343.405 | Volume: 543.625 |
Hydrophobic surface: 741.19 | Hydrophilic surface: 148.118 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |