Physical Properties | | | |
Molecular Weight: 472.286 g/mol | logS: -5.65464 | SlogP: 2.49294 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0989038 | Sterimol/B1: 3.26555 | Sterimol/B2: 3.65919 | Sterimol/B3: 4.91646 |
Sterimol/B4: 7.83113 | Sterimol/L: 14.4855 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 550.707 | Positive charged surface: 278.435 | Negative charged surface: 272.272 | Volume: 344.25 |
Hydrophobic surface: 404.274 | Hydrophilic surface: 146.433 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 6 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |