Physical Properties | | | |
Molecular Weight: 482.462 g/mol | logS: -2.53963 | SlogP: 0.5019 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.112917 | Sterimol/B1: 4.2517 | Sterimol/B2: 4.6902 | Sterimol/B3: 6.82302 |
Sterimol/B4: 8.25306 | Sterimol/L: 17.7509 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 786.356 | Positive charged surface: 509.334 | Negative charged surface: 277.021 | Volume: 430.75 |
Hydrophobic surface: 584.659 | Hydrophilic surface: 201.697 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |