Physical Properties | | | |
Molecular Weight: 456.108 g/mol | logS: -7.68778 | SlogP: 6.01829 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.338895 | Sterimol/B1: 3.94866 | Sterimol/B2: 5.79895 | Sterimol/B3: 6.14159 |
Sterimol/B4: 7.09245 | Sterimol/L: 13.4569 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 598.786 | Positive charged surface: 211.25 | Negative charged surface: 387.536 | Volume: 356.75 |
Hydrophobic surface: 435.366 | Hydrophilic surface: 163.42 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |