Physical Properties | | | |
Molecular Weight: 427.783 g/mol | logS: -5.80529 | SlogP: 3.8244 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.108852 | Sterimol/B1: 2.42443 | Sterimol/B2: 3.39917 | Sterimol/B3: 3.95549 |
Sterimol/B4: 13.202 | Sterimol/L: 14.7359 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 700.075 | Positive charged surface: 373.73 | Negative charged surface: 316.645 | Volume: 390.5 |
Hydrophobic surface: 494.185 | Hydrophilic surface: 205.89 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |