Physical Properties | | | |
Molecular Weight: 298.295 g/mol | logS: -0.39472 | SlogP: -1.8723 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0564421 | Sterimol/B1: 2.58787 | Sterimol/B2: 4.01862 | Sterimol/B3: 4.16188 |
Sterimol/B4: 4.38798 | Sterimol/L: 17.2655 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 514.87 | Positive charged surface: 328.654 | Negative charged surface: 186.217 | Volume: 263.375 |
Hydrophobic surface: 285.623 | Hydrophilic surface: 229.247 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 8 | Hydrogen bond acceptors: 8 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |