Physical Properties | | | |
Molecular Weight: 298.295 g/mol | logS: -0.39472 | SlogP: -1.8723 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0619896 | Sterimol/B1: 2.75474 | Sterimol/B2: 3.73719 | Sterimol/B3: 4.14802 |
Sterimol/B4: 4.79535 | Sterimol/L: 17.3779 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 520.402 | Positive charged surface: 332.384 | Negative charged surface: 188.018 | Volume: 260.875 |
Hydrophobic surface: 266.546 | Hydrophilic surface: 253.856 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 8 | Hydrogen bond acceptors: 8 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |