Physical Properties | | | |
Molecular Weight: 253.319 g/mol | logS: -0.05317 | SlogP: -2.0402 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.102767 | Sterimol/B1: 2.2308 | Sterimol/B2: 2.46219 | Sterimol/B3: 4.21859 |
Sterimol/B4: 6.73142 | Sterimol/L: 14.2688 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 468.306 | Positive charged surface: 366.847 | Negative charged surface: 101.459 | Volume: 226.125 |
Hydrophobic surface: 269.776 | Hydrophilic surface: 198.53 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |