Physical Properties | | | |
Molecular Weight: 411.977 g/mol | logS: -5.78402 | SlogP: 6.1165 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0557626 | Sterimol/B1: 2.32482 | Sterimol/B2: 4.60045 | Sterimol/B3: 5.01976 |
Sterimol/B4: 10.0642 | Sterimol/L: 16.5256 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 706.796 | Positive charged surface: 471.835 | Negative charged surface: 226.842 | Volume: 411.125 |
Hydrophobic surface: 635.449 | Hydrophilic surface: 71.347 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |