Physical Properties | | | |
Molecular Weight: 467.347 g/mol | logS: -6.02929 | SlogP: 4.9394 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0548891 | Sterimol/B1: 2.806 | Sterimol/B2: 3.81049 | Sterimol/B3: 5.28472 |
Sterimol/B4: 6.66789 | Sterimol/L: 17.8319 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 655.304 | Positive charged surface: 375.032 | Negative charged surface: 276.369 | Volume: 382.875 |
Hydrophobic surface: 516.626 | Hydrophilic surface: 138.678 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |