Physical Properties | | | |
Molecular Weight: 436.379 g/mol | logS: -7.67096 | SlogP: 6.6687 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.103338 | Sterimol/B1: 2.755 | Sterimol/B2: 4.40869 | Sterimol/B3: 4.79672 |
Sterimol/B4: 9.28349 | Sterimol/L: 14.992 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 605.743 | Positive charged surface: 266.602 | Negative charged surface: 324.658 | Volume: 353.25 |
Hydrophobic surface: 261.222 | Hydrophilic surface: 344.521 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 0 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |