Physical Properties | | | |
Molecular Weight: 320.172 g/mol | logS: -2.84949 | SlogP: 1.7188 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.13738 | Sterimol/B1: 3.06741 | Sterimol/B2: 4.55895 | Sterimol/B3: 4.72995 |
Sterimol/B4: 6.19664 | Sterimol/L: 13.5071 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 512.88 | Positive charged surface: 254.707 | Negative charged surface: 258.172 | Volume: 273.875 |
Hydrophobic surface: 247.512 | Hydrophilic surface: 265.368 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |