Physical Properties | | | |
Molecular Weight: 438.696 g/mol | logS: -11.4866 | SlogP: 8.37358 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.283179 | Sterimol/B1: 2.93265 | Sterimol/B2: 4.91178 | Sterimol/B3: 7.38795 |
Sterimol/B4: 7.4853 | Sterimol/L: 15.289 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 737.895 | Positive charged surface: 506.746 | Negative charged surface: 231.149 | Volume: 487.25 |
Hydrophobic surface: 537.854 | Hydrophilic surface: 200.041 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |