Physical Properties | | | |
Molecular Weight: 457.614 g/mol | logS: -6.17097 | SlogP: 6.2565 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.122488 | Sterimol/B1: 2.64913 | Sterimol/B2: 3.65742 | Sterimol/B3: 7.74642 |
Sterimol/B4: 9.22082 | Sterimol/L: 17.7229 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 753.625 | Positive charged surface: 566.014 | Negative charged surface: 187.611 | Volume: 463.375 |
Hydrophobic surface: 700.584 | Hydrophilic surface: 53.041 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |