Physical Properties | | | |
Molecular Weight: 395.978 g/mol | logS: -6.18241 | SlogP: 6.4776 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.14775 | Sterimol/B1: 3.76206 | Sterimol/B2: 4.02333 | Sterimol/B3: 5.99579 |
Sterimol/B4: 10.5498 | Sterimol/L: 17.2832 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 722.191 | Positive charged surface: 431.314 | Negative charged surface: 280.312 | Volume: 409.375 |
Hydrophobic surface: 634.708 | Hydrophilic surface: 87.483 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |