Physical Properties | | | |
Molecular Weight: 318.369 g/mol | logS: -2.04967 | SlogP: 0.2544 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.155426 | Sterimol/B1: 2.54454 | Sterimol/B2: 3.95592 | Sterimol/B3: 4.06028 |
Sterimol/B4: 8.22207 | Sterimol/L: 15.4745 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 554.163 | Positive charged surface: 342.267 | Negative charged surface: 211.896 | Volume: 306.625 |
Hydrophobic surface: 389.325 | Hydrophilic surface: 164.838 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |