Physical Properties | | | |
Molecular Weight: 424.649 g/mol | logS: -7.78624 | SlogP: 6.1434 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.178562 | Sterimol/B1: 2.71284 | Sterimol/B2: 4.43677 | Sterimol/B3: 5.03681 |
Sterimol/B4: 10.7601 | Sterimol/L: 16.4143 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 753.823 | Positive charged surface: 563.577 | Negative charged surface: 190.245 | Volume: 468.5 |
Hydrophobic surface: 612.205 | Hydrophilic surface: 141.618 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |