Physical Properties | | | |
Molecular Weight: 430.548 g/mol | logS: -5.71431 | SlogP: 3.8923 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.301549 | Sterimol/B1: 2.76494 | Sterimol/B2: 4.22659 | Sterimol/B3: 7.53701 |
Sterimol/B4: 7.6151 | Sterimol/L: 12.9424 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 627.144 | Positive charged surface: 466.428 | Negative charged surface: 156.261 | Volume: 422.25 |
Hydrophobic surface: 592.502 | Hydrophilic surface: 34.642 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |