Physical Properties | | | |
Molecular Weight: 358.374 g/mol | logS: -4.64175 | SlogP: 2.0609 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.016916 | Sterimol/B1: 2.10974 | Sterimol/B2: 3.18663 | Sterimol/B3: 3.64835 |
Sterimol/B4: 5.7792 | Sterimol/L: 19.056 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 572.876 | Positive charged surface: 288.678 | Negative charged surface: 272.811 | Volume: 299.75 |
Hydrophobic surface: 309.783 | Hydrophilic surface: 263.093 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 6 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |