Physical Properties | | | |
Molecular Weight: 376.412 g/mol | logS: -5.21506 | SlogP: 3.74714 | Reactive groups: 1 |
| | | |
Topological Properties | | | |
Globularity: 0.287032 | Sterimol/B1: 1.98325 | Sterimol/B2: 2.49242 | Sterimol/B3: 7.68972 |
Sterimol/B4: 10.6335 | Sterimol/L: 15.5738 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 635.567 | Positive charged surface: 424.857 | Negative charged surface: 204.783 | Volume: 358 |
Hydrophobic surface: 553.032 | Hydrophilic surface: 82.535 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |