Physical Properties | | | |
Molecular Weight: 396.368 g/mol | logS: -6.28016 | SlogP: 6.428 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0629864 | Sterimol/B1: 2.91055 | Sterimol/B2: 4.40128 | Sterimol/B3: 4.93304 |
Sterimol/B4: 9.53577 | Sterimol/L: 16.3149 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 639.341 | Positive charged surface: 331.118 | Negative charged surface: 304.076 | Volume: 346.5 |
Hydrophobic surface: 490.437 | Hydrophilic surface: 148.904 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |