Physical Properties | | | |
Molecular Weight: 441.831 g/mol | logS: -7.07092 | SlogP: 4.35477 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0678168 | Sterimol/B1: 2.43459 | Sterimol/B2: 3.10001 | Sterimol/B3: 4.90149 |
Sterimol/B4: 9.70042 | Sterimol/L: 18.3506 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 688.677 | Positive charged surface: 362.797 | Negative charged surface: 325.88 | Volume: 372.125 |
Hydrophobic surface: 494.144 | Hydrophilic surface: 194.533 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |