Physical Properties | | | |
Molecular Weight: 373.429 g/mol | logS: -3.10207 | SlogP: 0.93337 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0769193 | Sterimol/B1: 2.29501 | Sterimol/B2: 3.28743 | Sterimol/B3: 5.50184 |
Sterimol/B4: 8.0026 | Sterimol/L: 19.6492 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 654.471 | Positive charged surface: 446.097 | Negative charged surface: 208.374 | Volume: 357.125 |
Hydrophobic surface: 402.669 | Hydrophilic surface: 251.802 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |