Physical Properties | | | |
Molecular Weight: 386.879 g/mol | logS: -5.59857 | SlogP: 4.78909 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.148697 | Sterimol/B1: 2.74015 | Sterimol/B2: 4.56077 | Sterimol/B3: 5.57281 |
Sterimol/B4: 7.53971 | Sterimol/L: 15.1668 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 600.189 | Positive charged surface: 382.498 | Negative charged surface: 217.441 | Volume: 364.125 |
Hydrophobic surface: 461.205 | Hydrophilic surface: 138.984 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |