Physical Properties | | | |
Molecular Weight: 406.077 g/mol | logS: -6.12419 | SlogP: 5.0121 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.013685 | Sterimol/B1: 2.18766 | Sterimol/B2: 3.59635 | Sterimol/B3: 5.768 |
Sterimol/B4: 6.02754 | Sterimol/L: 14.8254 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 554.464 | Positive charged surface: 215.345 | Negative charged surface: 333.554 | Volume: 296.5 |
Hydrophobic surface: 505.693 | Hydrophilic surface: 48.771 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |