Physical Properties | | | |
Molecular Weight: 314.298 g/mol | logS: -0.86098 | SlogP: -1.565 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0442667 | Sterimol/B1: 2.83852 | Sterimol/B2: 3.14191 | Sterimol/B3: 3.33168 |
Sterimol/B4: 7.60084 | Sterimol/L: 17.7938 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 567.907 | Positive charged surface: 405.48 | Negative charged surface: 162.427 | Volume: 272.375 |
Hydrophobic surface: 264.359 | Hydrophilic surface: 303.548 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |