Physical Properties | | | |
Molecular Weight: 393.442 g/mol | logS: -5.0339 | SlogP: 3.6983 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.223457 | Sterimol/B1: 4.03242 | Sterimol/B2: 5.23036 | Sterimol/B3: 5.32206 |
Sterimol/B4: 5.33508 | Sterimol/L: 15.4982 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 611.637 | Positive charged surface: 332.702 | Negative charged surface: 278.935 | Volume: 370.625 |
Hydrophobic surface: 519.42 | Hydrophilic surface: 92.217 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |