Physical Properties | | | |
Molecular Weight: 406.381 g/mol | logS: -4.70689 | SlogP: 2.497 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0611375 | Sterimol/B1: 2.32668 | Sterimol/B2: 3.80552 | Sterimol/B3: 3.86819 |
Sterimol/B4: 8.15389 | Sterimol/L: 19.307 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 625.525 | Positive charged surface: 352.319 | Negative charged surface: 273.205 | Volume: 324.75 |
Hydrophobic surface: 339.561 | Hydrophilic surface: 285.964 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |