Physical Properties | | | |
Molecular Weight: 353.378 g/mol | logS: -3.98343 | SlogP: 1.8068 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.11546 | Sterimol/B1: 3.15875 | Sterimol/B2: 3.87272 | Sterimol/B3: 5.13713 |
Sterimol/B4: 8.9557 | Sterimol/L: 15.3161 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 598.255 | Positive charged surface: 405.878 | Negative charged surface: 190.992 | Volume: 324 |
Hydrophobic surface: 436.684 | Hydrophilic surface: 161.571 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |