Physical Properties | | | |
Molecular Weight: 358.462 g/mol | logS: -4.21604 | SlogP: 4.1809 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0762869 | Sterimol/B1: 2.41607 | Sterimol/B2: 2.90444 | Sterimol/B3: 6.02178 |
Sterimol/B4: 6.63605 | Sterimol/L: 17.8766 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 595.336 | Positive charged surface: 366.676 | Negative charged surface: 228.66 | Volume: 337.375 |
Hydrophobic surface: 437.184 | Hydrophilic surface: 158.152 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |