Physical Properties | | | |
Molecular Weight: 381.475 g/mol | logS: -4.60632 | SlogP: 2.786 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.120425 | Sterimol/B1: 2.36683 | Sterimol/B2: 3.98352 | Sterimol/B3: 4.53389 |
Sterimol/B4: 8.9517 | Sterimol/L: 14.9512 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 640.925 | Positive charged surface: 432.49 | Negative charged surface: 208.435 | Volume: 379.75 |
Hydrophobic surface: 517.666 | Hydrophilic surface: 123.259 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |