Physical Properties | | | |
Molecular Weight: 386.374 g/mol | logS: -3.35491 | SlogP: 2.2569 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00986231 | Sterimol/B1: 2.38693 | Sterimol/B2: 2.5234 | Sterimol/B3: 3.32019 |
Sterimol/B4: 6.21518 | Sterimol/L: 23.5274 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.998 | Positive charged surface: 446.39 | Negative charged surface: 236.608 | Volume: 340.875 |
Hydrophobic surface: 444.172 | Hydrophilic surface: 238.826 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |