Physical Properties | | | |
Molecular Weight: 378.276 g/mol | logS: -4.89243 | SlogP: 3.9791 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0086997 | Sterimol/B1: 2.3742 | Sterimol/B2: 2.56473 | Sterimol/B3: 2.81532 |
Sterimol/B4: 5.8171 | Sterimol/L: 19.5999 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 585.526 | Positive charged surface: 258.487 | Negative charged surface: 327.039 | Volume: 290.75 |
Hydrophobic surface: 282.627 | Hydrophilic surface: 302.899 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |