Physical Properties | | | |
Molecular Weight: 393.508 g/mol | logS: -5.75797 | SlogP: 4.37242 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.2721 | Sterimol/B1: 2.2602 | Sterimol/B2: 3.22327 | Sterimol/B3: 7.29536 |
Sterimol/B4: 9.59925 | Sterimol/L: 13.9322 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 602.885 | Positive charged surface: 285.569 | Negative charged surface: 317.317 | Volume: 331.375 |
Hydrophobic surface: 500.206 | Hydrophilic surface: 102.679 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |