Physical Properties | | | |
Molecular Weight: 482.816 g/mol | logS: -6.86789 | SlogP: 5.3419 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.145962 | Sterimol/B1: 3.10407 | Sterimol/B2: 3.90461 | Sterimol/B3: 5.0028 |
Sterimol/B4: 6.94244 | Sterimol/L: 16.6864 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 612.807 | Positive charged surface: 151.693 | Negative charged surface: 461.114 | Volume: 354.375 |
Hydrophobic surface: 507.234 | Hydrophilic surface: 105.573 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |