Physical Properties | | | |
Molecular Weight: 322.364 g/mol | logS: -3.46298 | SlogP: 3.33975 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.105683 | Sterimol/B1: 2.55388 | Sterimol/B2: 3.8919 | Sterimol/B3: 3.92799 |
Sterimol/B4: 9.10503 | Sterimol/L: 16.619 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 598.136 | Positive charged surface: 357.18 | Negative charged surface: 240.956 | Volume: 313.125 |
Hydrophobic surface: 401.734 | Hydrophilic surface: 196.402 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |