Physical Properties | | | |
Molecular Weight: 414.506 g/mol | logS: -5.80075 | SlogP: 4.12862 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0905751 | Sterimol/B1: 3.52869 | Sterimol/B2: 3.86282 | Sterimol/B3: 5.28836 |
Sterimol/B4: 6.5275 | Sterimol/L: 19.1309 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 663.4 | Positive charged surface: 384.947 | Negative charged surface: 278.453 | Volume: 366.125 |
Hydrophobic surface: 520.497 | Hydrophilic surface: 142.903 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |