Physical Properties | | | |
Molecular Weight: 394.882 g/mol | logS: -6.63281 | SlogP: 5.0255 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.209288 | Sterimol/B1: 3.38913 | Sterimol/B2: 5.25183 | Sterimol/B3: 5.34075 |
Sterimol/B4: 7.23084 | Sterimol/L: 14.0651 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 583.091 | Positive charged surface: 269.922 | Negative charged surface: 313.169 | Volume: 349.25 |
Hydrophobic surface: 516.719 | Hydrophilic surface: 66.372 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |