Physical Properties | | | |
Molecular Weight: 381.65 g/mol | logS: -5.69822 | SlogP: 4.78822 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0376192 | Sterimol/B1: 2.2698 | Sterimol/B2: 4.02899 | Sterimol/B3: 4.16579 |
Sterimol/B4: 6.63206 | Sterimol/L: 17.6997 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 590.085 | Positive charged surface: 229.009 | Negative charged surface: 361.076 | Volume: 313.375 |
Hydrophobic surface: 523.206 | Hydrophilic surface: 66.879 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |